Recombinant Humanized Type III Collagen

Recombinant Humanized Type III Collagen
Molecular Biology Grade
Source: From yeast cells with cloned gene encoding genetically engineered Humanized III Collagen
Catalog Number:  
GPE012001: 28.6 kDa
GPE012002: 10.4 kDa
GPE012003: 55.9 kDa
GPE012004: 5 kDa
Molecular Formula:  C4H6N2O3R2.(C7H9N2O2R)n
CAS No.: 9064-67-9E.C: 618-608-5
Properties
Molecular mass5-55.9 kDa,
pI6.59
pH range5-8
Storage Temperature-20℃
FormLyophilized powder
Description
Type III collagen is one of the major structural proteins in the body, primarily found in the skin, blood vessels, and internal organs. It plays a crucial role in maintaining the structural integrity and elasticity of these tissues and is vital for wound healing and tissue repair. Recombinant humanized type III collagen is a synthetic form of collagen that closely mimics the natural type III collagen found in human connective tissues.  

Gproan Recombinant Humanized Type III Collagen is derived from yeast, offering a highly innovative solution for various applications. This advanced protein is water-soluble, demonstrating remarkable stability, and exceptional hydrophilic and moisturizing properties. Produced using cutting-edge protein engineering techniques on a highly efficient 28,000-liter yeast platform, this product represents the most cost-effective solution for the development and production of medical aesthetics and medical devices.  

The yeast-based expression system, combined with chromatographic purification, ensures a high-purity product free from bacterial endotoxins, leading to superior performance and enhanced user satisfaction. With its exceptional water solubility, stability, and unparalleled cost-effectiveness, our Recombinant Humanized Type III Collagen is the optimal choice for researchers and manufacturers in the fields of medical aesthetics and medical devices.  

Advantages:
Outstanding Hydrophilicity and Moisturizing Properties: This type of collagen is water-soluble, which makes it easy to formulate into various products. It also exhibits excellent stability, which is critical for maintaining its effectiveness over time, especially in therapeutic and cosmetic applications.
Humanized and Recombinant This collagen is designed to closely resemble the natural collagen in humans. It is produced through recombinant DNA technology, typically using a host organism like yeast. The yeast is genetically engineered to produce the human-like collagen, ensuring that the protein structure and function are similar to those found in the human body.
High Purity The production process for recombinant humanized type III collagen involves rigorous purification steps, often resulting in a product with very high purity.
Human Gene-Derived Fragments, Animal-Free This collagen is free from animal-derived contaminants and bacterial endotoxins, making it safer for use in medical and cosmetic applications.
Virus-Free, No Risk of Immunogenic Reactions Free from viral risks and immune rejection, promoting safety and compatibility. Ensures a high level of purity, meeting stringent quality standards.  

Applications
Medical Applications: Due to its biocompatibility and ability to promote wound healing, recombinant humanized type III collagen is widely used in tissue engineering, wound dressings, and as a biomaterial for implants and other medical devices.
Cosmetics: In the cosmetics industry, this collagen is valued for its moisturizing properties and ability to enhance skin elasticity, making it a popular ingredient in anti-aging products, moisturizers, and serums.
Tissue Engineering: It is used in the development of scaffolds for tissue regeneration, providing structural support for the growth of new tissues.
Purity and Quality
Purity: ≥95% SDS-PAGE
Protein content:  ≥90%
Bioburdens: ≤5cfu/g
Escherichia coli – Not Detected;
Staphylococcus aureus – Not Detected;
Pseudomonas aeruginosa – Not Detected;
Endotoxin: ≤10EU/mg  
Total Heavy Metals (Pb) ≤ 10ppm;
Arsenic (As)  ≤ 2ppm
Mercury (Hg)  ≤ 2ppm,
Lead (Pb)  ≤ 5ppm
Chromium (Cr)  ≤ 5ppm
Cadmium (Cd) ≤ 2ppm;
Preparation Notes
For your safety and health, please wear laboratory attire and use protective gloves and goggles during operation. This product is aseptic lyophilized powder and is prone to moisture absorption. Please store sealed and dry.
Storage-20℃ in dry condition
Stability/Shelf life 1 year
Precautions and Disclaimer
Safety Information: Collagen is generally considered safe for use in various applications. However, individuals with allergies to collagen or its sources, such as cattle, may experience allergic reactions. It is important to follow proper handling and storage procedures to minimize the risk of contamination or degradation. This product is for R&D use only, not for drug, household, or other uses.
a woman wearing safety glass doing experiment

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